I don’t know… depends if that is the pin you are plugging your PIR input into? What about your LED?
However, It is NOT one of the recommended pins (using GPIO numeration NOT the Dpin ones) to use when others are available
Or are you referring to using an ESP-01 device? (otherwise, ALL other ESP8266 devices are considered “standalone”) If so, then yes, since you only have a few pins available, try them and test for yourself.